| Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an α-tetralone derivative in the green walnut husks (Juglans regia L.) | |
| Department | 甘肃省天然药物重点实验室 |
Li C(李辰); Liu JX(柳军玺) ; Zhao L(赵亮); Di DL(邸多隆); Meng M(孟敏); Jiang SX(蒋生祥)
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| 2008 | |
| Source Publication | Journal of Pharmaceut-ical and Biomedical Analysis
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| ISSN | 0731-7085 |
| Volume | 48Pages:749-753 |
| Abstract | A fast capillary zone electrophoresis (CZE) method for the simultaneous determination of four cyclic diarylheptanoids (rhoiptelol, RH; juglanin A, JA; juglanin B, JB; juglanin C, JC) and an _-tetralone derivative (sclerone, SC) in the extract of the greenwalnut husks (Juglans regia L.)was developed. The optimized buffer was composed of 25mM sodium tetraborate at pH 10.3. The applied voltage was 20 kV and the capillary temperature was kept constant at 20 ◦C. The detection wavelength was set at 220nm using a photodiode array detection. The effects of several CE parameters, including pH value, buffer concentration,applied voltage and separation temperature on the separation were investigated systematically.Regression equations showed good linear relationships (correlation coefficients: 0.9996–0.9999) between the peak area of each compound (RH, JA, JB, JC and SC) and its concentration accordingly. The relative standard deviations (R.S.D.) of the migration time and peak areawere less than 0.57 and 3.44% (intra-day), and 0.97 and 3.71% (inter-day), respectively. The contents of the five active compounds in the green walnut husks (J. regia L.) from different origins were determined with satisfactory repeatability and recovery. |
| Keyword | JugL.ns Regia L. Diarylheptanoids Α-tetralone Derivative Capillary Zone Electrophoresis |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the “Hundred Talents Program”and “West Light Program” of Chinese Academy of Sciences;the National Natural Sciences Foundation of China (NSFCNo.20775083) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物工艺标准研究组 ; 药物分离材料研究组 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1392 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Di DL(邸多隆) |
| Recommended Citation GB/T 7714 | Li C,Liu JX,Zhao L,et al. Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an α-tetralone derivative in the green walnut husks (Juglans regia L.)[J]. Journal of Pharmaceut-ical and Biomedical Analysis,2008,48:749-753. |
| APA | 李辰,柳军玺,赵亮,邸多隆,孟敏,&蒋生祥.(2008).Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an α-tetralone derivative in the green walnut husks (Juglans regia L.).Journal of Pharmaceut-ical and Biomedical Analysis,48,749-753. |
| MLA | 李辰,et al."Capillary zone electrophoresis for separation and analysis of four diarylheptanoids and an α-tetralone derivative in the green walnut husks (Juglans regia L.)".Journal of Pharmaceut-ical and Biomedical Analysis 48(2008):749-753. |
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