| Flavonoids in the Poisonous Plant Oxytropis falcate | |
| Department | 甘肃省天然药物重点实验室 |
Chen WH(陈文豪); Wang R(王瑞) ; Shi YP(师彦平)
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| 2010 | |
| Source Publication | J. Nat. Prod.
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| ISSN | 0163-3864 |
| Volume | 73Pages:1398-1403 |
| Abstract | Three new flavonoids, oxytropisoflavans A (1) and B (2) and (6aR,11aR)-3,8-dihydroxy-9,10-dimethoxypterocarpan(3), together with 30 known flavonoids (4-33), were isolated from the aerial parts and roots of Oxytropis falcata. The absolute configurations of 3 and C-3 in 1 and 2 were deduced by circular dichroism. The structure of flavonoid 2 was confirmed by single-crystal X-ray diffraction analysis and that of flavonoid 3 by total synthesis of its racemate. Oxytropisoflavan A (1) is an unprecedented chalcan-isoflavan biflavonoid, whereas oxytropisoflavan B (2) possesses a rare modified A-ring. Pterocarpan 3 has good radical-scavenging activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Key Technology Research and Development Program of China (No. 2007BAI37B05);National Natural Science Foundation of China (No. NSFC 20621091) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1260 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Recommended Citation GB/T 7714 | Chen WH,Wang R,Shi YP. Flavonoids in the Poisonous Plant Oxytropis falcate[J]. J. Nat. Prod.,2010,73:1398-1403. |
| APA | 陈文豪,王瑞,&师彦平.(2010).Flavonoids in the Poisonous Plant Oxytropis falcate.J. Nat. Prod.,73,1398-1403. |
| MLA | 陈文豪,et al."Flavonoids in the Poisonous Plant Oxytropis falcate".J. Nat. Prod. 73(2010):1398-1403. |
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