Protein Resistance and pH-Responsive Controlled Release from the Modification of Single-Walled Carbon Nanotubes with a Double Polymer Layer | |
Department | 固体润滑国家重点实验室 |
Zhang, Guoxiang1; Jia, Xin1; Liu, Zhiyong1; Hu, Jiamei1; Ma, Zhiyuan1; Zhou F(周峰)2 | |
2013 | |
Source Publication | Macromolecular Bioscience |
ISSN | 1616-5187 |
Volume | 13Issue:9Pages:1259-1266 |
Abstract | A reliable and easy method is developed to confer protein resistance and drug controlled release dual functions to single-walled carbon nanotubes (SWNTs) by modification with a polydopamine (Pdop) layer and poly(oligo(ethylene glycol) methacrylate) (POEGMA) brushes. The study of protein resistance demonstrates that POEGMA-modified SWNTs exhibit higher protein resistance than pristine SWNTs, and the protein resistance ability is dependant on the length of the POEGMA molecule. Furthermore, the Pdop layer can serve as a pH-responsive switch for controlled loading and release of rhodamine 6G. The integration of protein resistance and pH-responsive controlled release make the double-layer modified SWNTs attractive for drug delivery in cancer therapy. |
Keyword | Controlled Release Ph-responsivity Protein Resistance Single-walled Carbon Nanotubes Surface Modification |
Subject Area | 材料科学与物理化学 |
DOI | 10.1002/mabi.201300157 |
Indexed By | SCI |
If | 3.650 |
Language | 英语 |
Funding Project | 材料表面与界面行为研究组 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/12391 |
Collection | 固体润滑国家重点实验室(LSL) |
Corresponding Author | Jia, Xin |
Affiliation | 1.Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832003, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Zhang, Guoxiang,Jia, Xin,Liu, Zhiyong,et al. Protein Resistance and pH-Responsive Controlled Release from the Modification of Single-Walled Carbon Nanotubes with a Double Polymer Layer[J]. Macromolecular Bioscience,2013,13(9):1259-1266. |
APA | Zhang, Guoxiang,Jia, Xin,Liu, Zhiyong,Hu, Jiamei,Ma, Zhiyuan,&Zhou F.(2013).Protein Resistance and pH-Responsive Controlled Release from the Modification of Single-Walled Carbon Nanotubes with a Double Polymer Layer.Macromolecular Bioscience,13(9),1259-1266. |
MLA | Zhang, Guoxiang,et al."Protein Resistance and pH-Responsive Controlled Release from the Modification of Single-Walled Carbon Nanotubes with a Double Polymer Layer".Macromolecular Bioscience 13.9(2013):1259-1266. |
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LZ01027436 .pdf(757KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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