| Tunability of anion binding strength based on acyl-thiourea receptors containing isatin group | |
| Department | 甘肃省天然药物重点实验室 |
Hu SZ(胡树振); Guo Y(郭勇) ; Xu J(徐健); Shao SJ(邵士俊)
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| 2009 | |
| Source Publication | Spectrochimica Acta Part A
 |
| ISSN | 1386-1425 |
| Volume | 72Pages:1043-1046 |
| Abstract | Some acyl-thiourea derivatives containing isatin group were synthesized and their interactions with anions were investigated using UV–vis spectroscopy and 1H NMR titrations in DMSO and DMSO-d6,respectively. These compounds have a same molecular framework, functionalising with different groups lead to different anion binding strength of these receptors. Receptor 1 showed a higher binding affinity for AcO− than for F−, due to the cooperative multiple hydrogen bond interactions of AcO− with the acyl-thiourea group and N–H group in the indole unit of receptor 1. Displacing the N–H proton in the indole unit with –CH3 group, receptor 2 showed no obviously discriminative responses for F−, AcO− and H2PO4− due to lack of such additional binding. In the case of receptor 3, which was functionalised with strong electron-withdrawing group, it showed selectively chromogenic response for F− based on double deprotonation of the receptor in DMSO, whereas AcO− and H2PO4− induced single deprotonation only. |
| Keyword | Anion Recognition Acyl-thiourea Anion Receptor Isatin |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | National Nature Science Foundation of China (Grant Nos. 20372067;20672121) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物分子识别研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1190 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shao SJ(邵士俊) |
| Recommended Citation GB/T 7714 | Hu SZ,Guo Y,Xu J,et al. Tunability of anion binding strength based on acyl-thiourea receptors containing isatin group[J]. Spectrochimica Acta Part A,2009,72:1043-1046. |
| APA | 胡树振,郭勇,徐健,&邵士俊.(2009).Tunability of anion binding strength based on acyl-thiourea receptors containing isatin group.Spectrochimica Acta Part A,72,1043-1046. |
| MLA | 胡树振,et al."Tunability of anion binding strength based on acyl-thiourea receptors containing isatin group".Spectrochimica Acta Part A 72(2009):1043-1046. |
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