| Selective determination of uric acid in the presence of ascorbic acid at poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode | |
| Department | 甘肃省天然药物重点实验室 |
Tang H(汤浩); Hu GZ(胡广志); Jiang SX(蒋生祥) ; Liu X(刘霞)
| |
| 2009 | |
| Source Publication | Journal of Applied Electrochemistry
 |
| ISSN | 0021-891X |
| Volume | 39Pages:2323-2328 |
| Abstract | The electrocatalytic behavior of uric acid has been investigated with a glassy carbon electrode modified with p-aminobenzene sulfonic acid through electrochemical polymerization. This resulting electrode shows an excellent electrocatalytic response to uric acid and ascorbic acid, with a peak-to-peak separation of 0.267 V in a 0.1 mol L-1 phosphate buffer solution (PBS) at pH 7.0. These results indicate that the proposed electrode can eliminate the serious interference of ascorbic acid, which coexists with uric acid in body fluids. Differential pulse voltammetry (DPV) was used for detecting uric acid with selectivity and sensitivity. The anodic peak current of uric acid was proportional to its concentration in the range of 1.2 9 10-7–8.0 9 10-4 mol L-1, with a detection limit of 4.0 9 10-8 mol L-1. The proposed method has been applied with satisfactory results to the determination of uric acid in human urine without any pretreatment. |
| Keyword | Glassy Carbon Electrode Electro-polymerization Uric Acid Ascorbic Acid Selective Determination |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Natural Science Foundation of China (20527005, 20775084);the Natural Science Foundation of Gansu Province, China (3YS051-A25-022) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物分离材料研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1183 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Jiang SX(蒋生祥) |
| Recommended Citation GB/T 7714 | Tang H,Hu GZ,Jiang SX,et al. Selective determination of uric acid in the presence of ascorbic acid at poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode[J]. Journal of Applied Electrochemistry,2009,39:2323-2328. |
| APA | 汤浩,胡广志,蒋生祥,&刘霞.(2009).Selective determination of uric acid in the presence of ascorbic acid at poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode.Journal of Applied Electrochemistry,39,2323-2328. |
| MLA | 汤浩,et al."Selective determination of uric acid in the presence of ascorbic acid at poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode".Journal of Applied Electrochemistry 39(2009):2323-2328. |
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